THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt; S. Wallace; E. J. Freireich; V. P. Chuang; E. M. Hersh; G. M. Mavligit

doi:10.1016/S0140-6736(81)91671-8

THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt, S. Wallace, E. J. Freireich, V. P. Chuang, E. M. Hersh, G. M. Mavligit

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Abstract

Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

Original language	English (US)
Pages (from-to)	349-351
Number of pages	3
Journal	The Lancet
Volume	317
Issue number	8216
DOIs	https://doi.org/10.1016/S0140-6736(81)91671-8
State	Published - Feb 14 1981
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1016/S0140-6736(81)91671-8

Cite this

@article{f0b60bcb1ccc4f6ea662ec58b0816b6d,

title = "THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER",

abstract = "Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).",

author = "Patt, {Y. Z.} and S. Wallace and Freireich, {E. J.} and Chuang, {V. P.} and Hersh, {E. M.} and Mavligit, {G. M.}",

year = "1981",

month = feb,

day = "14",

doi = "10.1016/S0140-6736(81)91671-8",

language = "English (US)",

volume = "317",

pages = "349--351",

journal = "The Lancet",

issn = "0140-6736",

publisher = "Elsevier Limited",

number = "8216",

}

TY - JOUR

T1 - THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

AU - Patt, Y. Z.

AU - Wallace, S.

AU - Freireich, E. J.

AU - Chuang, V. P.

AU - Hersh, E. M.

AU - Mavligit, G. M.

PY - 1981/2/14

Y1 - 1981/2/14

N2 - Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

AB - Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

UR - http://www.scopus.com/inward/record.url?scp=0019350450&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019350450&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(81)91671-8

DO - 10.1016/S0140-6736(81)91671-8

M3 - Article

C2 - 6162066

AN - SCOPUS:0019350450

SN - 0140-6736

VL - 317

SP - 349

EP - 351

JO - The Lancet

JF - The Lancet

IS - 8216

ER -

THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this