THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt; S. Wallace; E. J. Freireich; V. P. Chuang; E. M. Hersh; G. M. Mavligit

doi:10.1016/S0140-6736(81)91671-8

THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Y. Z. Patt, S. Wallace, E. J. Freireich, V. P. Chuang, E. M. Hersh, G. M. Mavligit

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Abstract

Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

Original language	English (US)
Pages (from-to)	349-351
Number of pages	3
Journal	The Lancet
Volume	317
Issue number	8216
DOIs	https://doi.org/10.1016/S0140-6736(81)91671-8
State	Published - Feb 14 1981
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER",

abstract = "Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).",

author = "Patt, {Y. Z.} and S. Wallace and Freireich, {E. J.} and Chuang, {V. P.} and Hersh, {E. M.} and Mavligit, {G. M.}",

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AU - Wallace, S.

AU - Freireich, E. J.

AU - Chuang, V. P.

AU - Hersh, E. M.

AU - Mavligit, G. M.

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N2 - Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

AB - Fifty-five patients with metastatic colorectal carcinoma confined to the liver were treated with hepatic arterial infusion of floxuridine and mitomycin C. Tumour response rate was 43·4% and median overall survival was 11 months. Prolonged survival was associated with intentional or inadvertent occlusion of the hepatic artery. The median survival of twenty-four patients with arterial occlusion (15 months) was significantly higher than that of thirty-one patients without arterial occlusion (8 months).

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THE PALLIATIVE ROLE OF HEPATIC ARTERIAL INFUSION AND ARTERIAL OCCLUSION IN COLORECTAL CARCINOMA METASTATIC TO THE LIVER

Abstract

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