The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum

M. Goedert; S. P. Hunt; P. W. Mantyh; P. C. Emson

doi:10.1016/0165-3806(85)90095-1

The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum

M. Goedert, S. P. Hunt, P. W. Mantyh, P. C. Emson

Pharmacology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

At birth, striatal neurotensin-like immunoreactivity amounted to 10% of the adult values which were reached at the age of 5 weeks. In the caudate nucleus neurotensin-like immunoreactivity presented a patchy distribution throughout development that was in register with Met-enkephalin straining, whereas [³H]neurotensin binding sites were most heavily concentrated in the background matrix. Thus, the adult distribution pattern of neurotensin-like immunoreactivity and ]³H]neurotensin binding sites is already established at birth.

Original language	English (US)
Pages (from-to)	127-131
Number of pages	5
Journal	Developmental Brain Research
Volume	20
Issue number	1
DOIs	https://doi.org/10.1016/0165-3806(85)90095-1
State	Published - May 1985

Keywords

development
neurotensin receptors
neurotensin-like immunoreactivity
striosomes

ASJC Scopus subject areas

Developmental Neuroscience
Developmental Biology

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10.1016/0165-3806(85)90095-1

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abstract = "At birth, striatal neurotensin-like immunoreactivity amounted to 10% of the adult values which were reached at the age of 5 weeks. In the caudate nucleus neurotensin-like immunoreactivity presented a patchy distribution throughout development that was in register with Met-enkephalin straining, whereas [3H]neurotensin binding sites were most heavily concentrated in the background matrix. Thus, the adult distribution pattern of neurotensin-like immunoreactivity and ]3H]neurotensin binding sites is already established at birth.",

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AU - Emson, P. C.

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AB - At birth, striatal neurotensin-like immunoreactivity amounted to 10% of the adult values which were reached at the age of 5 weeks. In the caudate nucleus neurotensin-like immunoreactivity presented a patchy distribution throughout development that was in register with Met-enkephalin straining, whereas [3H]neurotensin binding sites were most heavily concentrated in the background matrix. Thus, the adult distribution pattern of neurotensin-like immunoreactivity and ]3H]neurotensin binding sites is already established at birth.

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The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum

Abstract

Keywords

ASJC Scopus subject areas

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