Abstract
Phonological deficits are common in aphasia after left-hemisphere stroke, and can have significant functional consequences for spoken and written language. While many individuals improve through treatment, the neural substrates supporting improvements are poorly understood. We measured brain activation during pseudoword reading in an individual through two treatment phases. Improvements were associated with greater activation in residual left dorsal language regions and bilateral regions supporting attention and effort. Gains were maintained, while activation returned to pre-treatment levels. This case demonstrates the neural support for improved phonology after damage to critical regions and that improvements may be maintained without markedly increased effort.
Original language | English (US) |
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Pages (from-to) | 31-40 |
Number of pages | 10 |
Journal | Neurocase |
Volume | 24 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2 2018 |
Keywords
- Acquired alexia
- acquired agraphia
- aphasia
- functional MRI
- phonological impairment
- rehabilitation
ASJC Scopus subject areas
- Arts and Humanities (miscellaneous)
- Clinical Neurology