The Need for Ventilatory Support During Bystander CPR

Robert A. Berg, David Wilcoxson, Ronald W. Hilwig, Karl B. Kern, Arthur B. Sanders, Charles W. Otto, Diane K. Eklund, Gordon A. Ewy

Research output: Contribution to journalArticlepeer-review

115 Scopus citations


Study objective: To compare CPR with chest compressions plus ventilatory support (CC+V) and chest compressions alone (CC). Design: Prospective, randomized study. Setting: Research laboratory. Interventions: After 2 minutes of ventricular fibrillation, 18 domestic swine (20 to 35 kg) were treated first with CC or CC+V for 10 minutes, then with standard advanced cardiac life support. Results: Hemodynamics, survival, and neurologic outcome were determined. All 8 swine subjected to CC+V and all 10 subjected to CC showed return of spontaneous circulation. One animal in each group died within 1 hour. Seven of 8 animals in the CC+V group survived for 24 and 48 hours, compared with 9 of 10 CC animals at 24 hours and 8 of 10 at 48 hours. All 48-hour survivors were neurologically normal. Conclusion: In this experimental model of bystander CPR, we could not detect a difference in hemodynamics, 48-hour survival, or neurologic outcome when CPR was applied with and without ventilatory support. [Berg RA, Wilcoxson D, Hilwig RW, Kern KB, Sanders AB, Otto CW, Eklund DK, Ewy GA: The need for ventilatory support during bystander CPR. Ann Emerg Med September 1995;26:342-350.].

Original languageEnglish (US)
Pages (from-to)342-349
Number of pages8
JournalAnnals of emergency medicine
Issue number3
StatePublished - Sep 1995

ASJC Scopus subject areas

  • Emergency Medicine


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