The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Neil M. Ampel; Daniel K. Nelson; Lijin Li; Sara O. Dionne; Douglas F. Lake; Keira A. Simmons; Demosthenes Pappagianis

doi:10.1128/IAI.73.4.2554-2555.2005

The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Neil M. Ampel, Daniel K. Nelson, Lijin Li, Sara O. Dionne, Douglas F. Lake, Keira A. Simmons, Demosthenes Pappagianis

Medicine

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

Original language	English (US)
Pages (from-to)	2554-2555
Number of pages	2
Journal	Infection and Immunity
Volume	73
Issue number	4
DOIs	https://doi.org/10.1128/IAI.73.4.2554-2555.2005
State	Published - Apr 2005

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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abstract = "Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.",

author = "Ampel, \{Neil M.\} and Nelson, \{Daniel K.\} and Lijin Li and Dionne, \{Sara O.\} and Lake, \{Douglas F.\} and Simmons, \{Keira A.\} and Demosthenes Pappagianis",

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AU - Ampel, Neil M.

AU - Nelson, Daniel K.

AU - Li, Lijin

AU - Dionne, Sara O.

AU - Lake, Douglas F.

AU - Simmons, Keira A.

AU - Pappagianis, Demosthenes

PY - 2005/4

Y1 - 2005/4

N2 - Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

AB - Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

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U2 - 10.1128/IAI.73.4.2554-2555.2005

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AN - SCOPUS:16244370984

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JO - Infection and Immunity

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IS - 4

ER -

The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Abstract

ASJC Scopus subject areas

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