Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.
|Original language||English (US)|
|Number of pages||2|
|Journal||Infection and Immunity|
|State||Published - Apr 2005|
ASJC Scopus subject areas
- Infectious Diseases