The mammalian pseudoautosomal region

N. Ellis; P. N. Goodfellow

doi:10.1016/0168-9525(89)90199-6

The mammalian pseudoautosomal region

N. Ellis, P. N. Goodfellow

Research output: Contribution to journal › Article › peer-review

116 Scopus citations

Abstract

Despite being mophologically dissimilar, mammalian sex chromosomes pair in male meiosis. Molecular studies of the X and Y chromosomes in humans and mice have identified the pseudoautosomal region, a genetically unique region of shared, recombining sequences that fall within the meiotic pairing region. Complete meiotic and physical maps of the human pseudoautosomal region have been produced and the pseudoautosomal boundary has been cloned and sequenced. These studies have provided clues to mammalian sex chromosome function and evolution.

Original language	English (US)
Pages (from-to)	406-410
Number of pages	5
Journal	Trends in Genetics
Volume	5
Issue number	C
DOIs	https://doi.org/10.1016/0168-9525(89)90199-6
State	Published - 1989
Externally published	Yes

ASJC Scopus subject areas

Genetics

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10.1016/0168-9525(89)90199-6

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title = "The mammalian pseudoautosomal region",

abstract = "Despite being mophologically dissimilar, mammalian sex chromosomes pair in male meiosis. Molecular studies of the X and Y chromosomes in humans and mice have identified the pseudoautosomal region, a genetically unique region of shared, recombining sequences that fall within the meiotic pairing region. Complete meiotic and physical maps of the human pseudoautosomal region have been produced and the pseudoautosomal boundary has been cloned and sequenced. These studies have provided clues to mammalian sex chromosome function and evolution.",

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AB - Despite being mophologically dissimilar, mammalian sex chromosomes pair in male meiosis. Molecular studies of the X and Y chromosomes in humans and mice have identified the pseudoautosomal region, a genetically unique region of shared, recombining sequences that fall within the meiotic pairing region. Complete meiotic and physical maps of the human pseudoautosomal region have been produced and the pseudoautosomal boundary has been cloned and sequenced. These studies have provided clues to mammalian sex chromosome function and evolution.

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The mammalian pseudoautosomal region

Abstract

ASJC Scopus subject areas

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