The liver—spleen scan in systemic amyloidosis: A clue to the diagnosis

Robert F. Straub, Thomas D. Boyer

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The clinical findings in cirrhosis and systemic amyloidosis may be similar, leading to difficulties in diagnosis. We studied three patients with systemic amyloidosis with a 99mTc sulfur colloid liver-spleen scan. In all three patients, uptake by the spleen was less than the liver, in contrast with the increased splenic uptake seen in patients with cirrhosis. The liver-spleen scan may be a useful tool in differentiating patients with cirrhosis from those with systemic amyloidosis when clinical findings fail to give the proper diagnosis.

Original languageEnglish (US)
Pages (from-to)340-343
Number of pages4
JournalJournal of clinical gastroenterology
Issue number4
StatePublished - Jun 1993
Externally publishedYes


  • Amyloidosis
  • Liver
  • Spleen scan

ASJC Scopus subject areas

  • Gastroenterology


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