The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent

Maha Zewail-Foote, Ven Shun Li, Harold Kohn, David Bearss, Mary Guzman, Laurence H. Hurley

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Fingerprint

Dive into the research topics of 'The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent'. Together they form a unique fingerprint.

Medicine & Life Sciences

Chemical Compounds