The Employment of Sodium Hydride as a Michael Donor in Palladium-catalyzed Reductions of α, β-Unsaturated Carbonyl Compounds

Ye Liu, Yujian Mao, Yanwei Hu, Jingjing Gui, Liang Wang, Wei Wang, Shilei Zhang

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Sodium hydride was employed as a Michael donor under the catalysis of PdCl 2 for 1,4-conjugate reductions of α, β-unsaturated carbonyl compounds, which features operational simplicity, mild conditions and high atom-economy. The merits of NaH as a reductant were demonstrated by the one-pot or cascade reactions for the syntheses of complex molecules. (Figure presented.).

Original languageEnglish (US)
Pages (from-to)1554-1558
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume361
Issue number7
DOIs
StatePublished - Apr 1 2019
Externally publishedYes

Keywords

  • 1,4-conjugate reduction
  • Michael donor
  • palladium catalysis
  • sodium hydride
  • α, β-unsaturated carbonyl compounds

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'The Employment of Sodium Hydride as a Michael Donor in Palladium-catalyzed Reductions of α, β-Unsaturated Carbonyl Compounds'. Together they form a unique fingerprint.

Cite this