The effects of organophosphate pesticide exposure on Hispanic children's cognitive and behavioral functioning

Patricia Sánchez Lizardi; Mary Kay O'Rourke; Richard J. Morris

doi:10.1093/jpepsy/jsm047

The effects of organophosphate pesticide exposure on Hispanic children's cognitive and behavioral functioning

Patricia Sánchez Lizardi, Mary Kay O'Rourke, Richard J. Morris

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Objective: This study investigates the effects of Organophosphate (OP) pesticides exposure on the cognitive and behavioral functioning of Hispanic children living in an agricultural community. Methods: Forty-eight children were administered a battery of cognitive measures, and their parents and teachers completed behavior rating scales. Children provided a urine sample for analysis of OP pesticides metabolites. Results: All children had a detectable level of at least one OP pesticide metabolite. Higher OP pesticide metabolite concentration levels were significantly correlated with poorer performance on some subtests of the Wisconsin Card Sorting Test. However, the significance of this association was dependent upon the inclusion of two samples with noticeable higher OP pesticide metabolite concentration levels. Conclusions: Short-term OP pesticide exposure seems to have deleterious effects on children's speed of attention, sequencing, mental flexibility, visual search, concept formation, and conceptual flexibility. This study is among a relatively small number of studies investigating an extremely complex problem. Limitations and suggestions for future studies are discussed.

Original language	English (US)
Pages (from-to)	91-101
Number of pages	11
Journal	Journal of pediatric psychology
Volume	33
Issue number	1
DOIs	https://doi.org/10.1093/jpepsy/jsm047
State	Published - 2008

Keywords

Children's cognitive and behavioral functioning
Organophosphates
Pesticides exposure

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental and Educational Psychology

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10.1093/jpepsy/jsm047

Cite this

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title = "The effects of organophosphate pesticide exposure on Hispanic children's cognitive and behavioral functioning",

abstract = "Objective: This study investigates the effects of Organophosphate (OP) pesticides exposure on the cognitive and behavioral functioning of Hispanic children living in an agricultural community. Methods: Forty-eight children were administered a battery of cognitive measures, and their parents and teachers completed behavior rating scales. Children provided a urine sample for analysis of OP pesticides metabolites. Results: All children had a detectable level of at least one OP pesticide metabolite. Higher OP pesticide metabolite concentration levels were significantly correlated with poorer performance on some subtests of the Wisconsin Card Sorting Test. However, the significance of this association was dependent upon the inclusion of two samples with noticeable higher OP pesticide metabolite concentration levels. Conclusions: Short-term OP pesticide exposure seems to have deleterious effects on children's speed of attention, sequencing, mental flexibility, visual search, concept formation, and conceptual flexibility. This study is among a relatively small number of studies investigating an extremely complex problem. Limitations and suggestions for future studies are discussed.",

keywords = "Children's cognitive and behavioral functioning, Organophosphates, Pesticides exposure",

author = "{S{\'a}nchez Lizardi}, Patricia and O'Rourke, {Mary Kay} and Morris, {Richard J.}",

note = "Funding Information: This work is derived from the first author{\textquoteright}s dissertation, which was submitted to the University of Arizona. This research was supported by EPA STAR grants no. R825169 and no. R827443 to the University of Arizona (Mary Kay O{\textquoteright}Rourke, PhD, Principal Investigator) and the David and Minnie Meyerson Foundation{\textquoteright}s {\textquoteleft}{\textquoteleft}Project on Research, Advocacy, and Policy Studies on Disability{\textquoteright}{\textquoteright} (Richard J. Morris, PhD, Project Director). The authors want to thank all the children, families, and community members of Yuma County, Arizona for their participation in this study. Although the research described in this aritcle has been funded in part by the United States Environmental Protection Agency through EPA STAR grants, it has not been subjected to agency review and therefore does not necessarily reflect the views of the agency, and no official endorsement should be inferred.",

year = "2008",

doi = "10.1093/jpepsy/jsm047",

language = "English (US)",

volume = "33",

pages = "91--101",

journal = "Journal of Pediatric Psychology",

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AU - Sánchez Lizardi, Patricia

AU - O'Rourke, Mary Kay

AU - Morris, Richard J.

N1 - Funding Information: This work is derived from the first author’s dissertation, which was submitted to the University of Arizona. This research was supported by EPA STAR grants no. R825169 and no. R827443 to the University of Arizona (Mary Kay O’Rourke, PhD, Principal Investigator) and the David and Minnie Meyerson Foundation’s ‘‘Project on Research, Advocacy, and Policy Studies on Disability’’ (Richard J. Morris, PhD, Project Director). The authors want to thank all the children, families, and community members of Yuma County, Arizona for their participation in this study. Although the research described in this aritcle has been funded in part by the United States Environmental Protection Agency through EPA STAR grants, it has not been subjected to agency review and therefore does not necessarily reflect the views of the agency, and no official endorsement should be inferred.

PY - 2008

Y1 - 2008

N2 - Objective: This study investigates the effects of Organophosphate (OP) pesticides exposure on the cognitive and behavioral functioning of Hispanic children living in an agricultural community. Methods: Forty-eight children were administered a battery of cognitive measures, and their parents and teachers completed behavior rating scales. Children provided a urine sample for analysis of OP pesticides metabolites. Results: All children had a detectable level of at least one OP pesticide metabolite. Higher OP pesticide metabolite concentration levels were significantly correlated with poorer performance on some subtests of the Wisconsin Card Sorting Test. However, the significance of this association was dependent upon the inclusion of two samples with noticeable higher OP pesticide metabolite concentration levels. Conclusions: Short-term OP pesticide exposure seems to have deleterious effects on children's speed of attention, sequencing, mental flexibility, visual search, concept formation, and conceptual flexibility. This study is among a relatively small number of studies investigating an extremely complex problem. Limitations and suggestions for future studies are discussed.

AB - Objective: This study investigates the effects of Organophosphate (OP) pesticides exposure on the cognitive and behavioral functioning of Hispanic children living in an agricultural community. Methods: Forty-eight children were administered a battery of cognitive measures, and their parents and teachers completed behavior rating scales. Children provided a urine sample for analysis of OP pesticides metabolites. Results: All children had a detectable level of at least one OP pesticide metabolite. Higher OP pesticide metabolite concentration levels were significantly correlated with poorer performance on some subtests of the Wisconsin Card Sorting Test. However, the significance of this association was dependent upon the inclusion of two samples with noticeable higher OP pesticide metabolite concentration levels. Conclusions: Short-term OP pesticide exposure seems to have deleterious effects on children's speed of attention, sequencing, mental flexibility, visual search, concept formation, and conceptual flexibility. This study is among a relatively small number of studies investigating an extremely complex problem. Limitations and suggestions for future studies are discussed.

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The effects of organophosphate pesticide exposure on Hispanic children's cognitive and behavioral functioning

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