TY - JOUR
T1 - The effect of pH and complexation of amino acid functionality on the redox chemistry of methionine and X-Ray structure of [Co(en)2(L-Met)](ClO4)2.H2O
AU - Sanaullah,
AU - Wilson, George S.
AU - Glass, Richard S.
PY - 1994/8/1
Y1 - 1994/8/1
N2 - Anodic oxidation of methionine under different pH conditions is reported. The results are compared with the oxidation process when the glycinic terminus of methionine is coordinated with Co(III). Synthesis of [Co(en)2(L-Met)](ClO4)2, [Co(trien)(L-Met)](CF3SO3)2, and [Co(trien)(OSO2CF3)2]CF3SO3 is reported where L-Met = L-methionine, en = ethylenediamine, trien = triethylenetetraamine. The triflato complex ([Co(trien)(OSO2CF3)2]CF3SO3) can serve as a starting material for synthesizing a variety of complexes. The x-ray structure of [Co(en)2(L-Met)](ClO4)2.H2O is also presented The complex crystallizes in space group P21 of the mono-clinic system with two independent molecules in the crystallographic asymmetric unit. The unit cell dimensions are a = 9.582 (2) Å, b = 11.554 (2) Å, c = 19.988 (6) Å, and f = 98.85 (2)°. The two molecular units are related by a pseudo-center of symmetry. The electrochemical data presented here suggest a major role of the neighboring group and pH in defining the ease of oxidation of methionine.
AB - Anodic oxidation of methionine under different pH conditions is reported. The results are compared with the oxidation process when the glycinic terminus of methionine is coordinated with Co(III). Synthesis of [Co(en)2(L-Met)](ClO4)2, [Co(trien)(L-Met)](CF3SO3)2, and [Co(trien)(OSO2CF3)2]CF3SO3 is reported where L-Met = L-methionine, en = ethylenediamine, trien = triethylenetetraamine. The triflato complex ([Co(trien)(OSO2CF3)2]CF3SO3) can serve as a starting material for synthesizing a variety of complexes. The x-ray structure of [Co(en)2(L-Met)](ClO4)2.H2O is also presented The complex crystallizes in space group P21 of the mono-clinic system with two independent molecules in the crystallographic asymmetric unit. The unit cell dimensions are a = 9.582 (2) Å, b = 11.554 (2) Å, c = 19.988 (6) Å, and f = 98.85 (2)°. The two molecular units are related by a pseudo-center of symmetry. The electrochemical data presented here suggest a major role of the neighboring group and pH in defining the ease of oxidation of methionine.
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U2 - 10.1016/0162-0134(94)85031-3
DO - 10.1016/0162-0134(94)85031-3
M3 - Article
C2 - 8051543
AN - SCOPUS:0028338885
SN - 0162-0134
VL - 55
SP - 87
EP - 99
JO - Journal of Inorganic Biochemistry
JF - Journal of Inorganic Biochemistry
IS - 2
ER -