Abstract
The Rho protein is a toroid-shaped oligomeric ATPase that catalyses thet release of nascent RNA transcripts at discrete sites within the transcription units of E. coli and many coliphages. The signal that specifies the location of the Rho-mediated termination event appears to be quite complex. Multiple sites for Rho-subunit attachment are superimposed on a large region of the RNA transcript that contains little or no secondary structure. RNA polymerase pause sites and template-transcript interactions may also serve to define the actual locations of transcript release.
Original language | English (US) |
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Pages (from-to) | 343-347 |
Number of pages | 5 |
Journal | Trends in Biochemical Sciences |
Volume | 13 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1988 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology