The deep population history of northern East Asia from the Late Pleistocene to the Holocene

Xiaowei Mao, Hucai Zhang, Shiyu Qiao, Yichen Liu, Fengqin Chang, Ping Xie, Ming Zhang, Tianyi Wang, Mian Li, Peng Cao, Ruowei Yang, Feng Liu, Qingyan Dai, Xiaotian Feng, Wanjing Ping, Chuzhao Lei, John W. Olsen, E. Andrew Bennett, Qiaomei Fu

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Northern East Asia was inhabited by modern humans as early as 40 thousand years ago (ka), as demonstrated by the Tianyuan individual. Using genome-wide data obtained from 25 individuals dated to 33.6–3.4 ka from the Amur region, we show that Tianyuan-related ancestry was widespread in northern East Asia before the Last Glacial Maximum (LGM). At the close of the LGM stadial, the earliest northern East Asian appeared in the Amur region, and this population is basal to ancient northern East Asians. Human populations in the Amur region have maintained genetic continuity from 14 ka, and these early inhabitants represent the closest East Asian source known for Ancient Paleo-Siberians. We also observed that EDAR V370A was likely to have been elevated to high frequency after the LGM, suggesting the possible timing for its selection. This study provides a deep look into the population dynamics of northern East Asia.

Original languageEnglish (US)
Pages (from-to)3256-3266.e13
JournalCell
Volume184
Issue number12
DOIs
StatePublished - Jun 10 2021

Keywords

  • Last Glacial Maximum
  • ancient DNA
  • northern East Asia
  • population dynamics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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