The coaction of tonic and phasic dopamine dynamics

Christopher W. Atcherley; Kevin M. Wood; Kate L. Parent; Parastoo Hashemi; Michael L. Heien

doi:10.1039/c4cc06165a

The coaction of tonic and phasic dopamine dynamics

Christopher W. Atcherley
, Kevin M. Wood
, Kate L. Parent
, Parastoo Hashemi
, Michael L. Heien

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10^-6 cm² s^-1) in the mouse brain.

Original language	English (US)
Pages (from-to)	2235-2238
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	12
DOIs	https://doi.org/10.1039/c4cc06165a
State	Published - Feb 11 2015

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c4cc06165a

Cite this

@article{d82267f7d760475c860be62f23ba8256,

title = "The coaction of tonic and phasic dopamine dynamics",

abstract = "Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10-6 cm2 s-1) in the mouse brain.",

author = "Atcherley, \{Christopher W.\} and Wood, \{Kevin M.\} and Parent, \{Kate L.\} and Parastoo Hashemi and Heien, \{Michael L.\}",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2015.",

year = "2015",

month = feb,

day = "11",

doi = "10.1039/c4cc06165a",

language = "English (US)",

volume = "51",

pages = "2235--2238",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "12",

}

TY - JOUR

T1 - The coaction of tonic and phasic dopamine dynamics

AU - Atcherley, Christopher W.

AU - Wood, Kevin M.

AU - Parent, Kate L.

AU - Hashemi, Parastoo

AU - Heien, Michael L.

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015/2/11

Y1 - 2015/2/11

N2 - Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10-6 cm2 s-1) in the mouse brain.

AB - Tonic neurochemical dopamine activity underlies many brain functions; however a consensus on this important concentration has not yet been reached. In this work, we introduce in vivo fast-scan controlled-adsorption voltammetry to report tonic dopamine concentrations (90 ± 9 nM) and the dopamine diffusion coefficient (1.05 ± 0.09 × 10-6 cm2 s-1) in the mouse brain.

UR - https://www.scopus.com/pages/publications/84921874617

UR - https://www.scopus.com/pages/publications/84921874617#tab=citedBy

U2 - 10.1039/c4cc06165a

DO - 10.1039/c4cc06165a

M3 - Article

C2 - 25249291

AN - SCOPUS:84921874617

SN - 1359-7345

VL - 51

SP - 2235

EP - 2238

JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -

The coaction of tonic and phasic dopamine dynamics

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this