TY - JOUR
T1 - The adverse health effects of biological aerosols, other aerosols, and indoor microclimate on asthmatics and nonasthmatics
AU - Lebowitz, Michael D.
AU - O'Rourke, Mary Kaye
AU - Dodge, Russell
AU - Holberg, Catharine J.
AU - Corman, Gregory
AU - Hoshaw, Robert W.
AU - Pinnas, Jack L.
AU - Barbee, Robert A.
AU - Sneller, Mark R.
N1 - Funding Information:
Acknowledgements-This work would not have been possible without the technical help of N. Mauney and J. Wang (Algae Lab), L. Toolin (Pollen Lab), T. Chien (Bacillus Lab), the health data collection team under B. Boyer (Chief Nurse Interviewer), the typing of L. Phipps, and the excellent advice of our consultants: Drs. A. Solomon (Oak Ridge) in Palynology, H. Thompson in Clinical Immunology, M. Halonen in Immunology, L. L. Fox and J. Moyers in Air Pollution Monitoring, and R. Knudson and B. Burrows in Pulmonary Medicine. This work was supported by EPA Grant No. R805318010 and NIH NHLBI SCOR Grant No. HL14136.
PY - 1982
Y1 - 1982
N2 - Asthmatic and nonasthmatic families in a representative community population sample have been monitored over a 2-year period using daily diaries. Simultaneous micro-indoor and outdoor monitoring has been conducted in a representative sample of houses for air pollutants, pollen, fungi, algae, and climate. Macromonitoring of air pollutants and pollen was conducted simultaneously. The relationship of indoor to outdoor and micro to macro factors can be demonstrated. Acute symptoms were strongly related to age, weakly related to sex, and not related to smoking habits. The qualitative relationship of these micro and macro factors to symptoms in asthmatic and nonasthmatic families have been explored. Suspended particulate matter and pollen were related to symptoms in asthmatics and nonasthmatics. Fungi might be related to symptoms as well. The use of gas stoves is qualitatively related to symptoms. Algae and other contaminants of evaporative coolers do not appear to be important in producing symptoms. More complex statistical analyses are required to determine interactions of these factors. Distinction has to be drawn between infectious episodes, allergic episodes, nonallergic but similar episodes, and asthmatic attacks. This study demonstrates the need for further investigations in this area.
AB - Asthmatic and nonasthmatic families in a representative community population sample have been monitored over a 2-year period using daily diaries. Simultaneous micro-indoor and outdoor monitoring has been conducted in a representative sample of houses for air pollutants, pollen, fungi, algae, and climate. Macromonitoring of air pollutants and pollen was conducted simultaneously. The relationship of indoor to outdoor and micro to macro factors can be demonstrated. Acute symptoms were strongly related to age, weakly related to sex, and not related to smoking habits. The qualitative relationship of these micro and macro factors to symptoms in asthmatic and nonasthmatic families have been explored. Suspended particulate matter and pollen were related to symptoms in asthmatics and nonasthmatics. Fungi might be related to symptoms as well. The use of gas stoves is qualitatively related to symptoms. Algae and other contaminants of evaporative coolers do not appear to be important in producing symptoms. More complex statistical analyses are required to determine interactions of these factors. Distinction has to be drawn between infectious episodes, allergic episodes, nonallergic but similar episodes, and asthmatic attacks. This study demonstrates the need for further investigations in this area.
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U2 - 10.1016/0160-4120(82)90053-8
DO - 10.1016/0160-4120(82)90053-8
M3 - Article
AN - SCOPUS:0020262186
SN - 0160-4120
VL - 8
SP - 375
EP - 380
JO - Environment international
JF - Environment international
IS - 1-6
ER -