TY - JOUR
T1 - Tension measurement in isolated rat and mouse pulmonary artery
AU - Ko, Eun A.
AU - Song, Michael Y.
AU - Donthamsetty, Reshma
AU - Makino, Ayako
AU - Yuan, Jason X.J.
N1 - Funding Information:
This work was supported in part by grants from the National Institutes of Health ( DK083506, HL066012 and HL098053 ).
PY - 2010
Y1 - 2010
N2 - Arterial vasoconstriction is an important physiological process in regulating blood pressure, and is involved in pathologies. The isolation of arteries from rats and mice, as well as the measurement of vascular tension in an ex vivo preparation, is an important method in studying the physiology of arteries and the pathophysiology associated with arterials. Three major methods to measure vascular tension are organ bath, wire myograph, and pressurized arterial myograph. The major method to measure vascular remodeling is by observing the zero-stress state of an artery.
AB - Arterial vasoconstriction is an important physiological process in regulating blood pressure, and is involved in pathologies. The isolation of arteries from rats and mice, as well as the measurement of vascular tension in an ex vivo preparation, is an important method in studying the physiology of arteries and the pathophysiology associated with arterials. Three major methods to measure vascular tension are organ bath, wire myograph, and pressurized arterial myograph. The major method to measure vascular remodeling is by observing the zero-stress state of an artery.
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U2 - 10.1016/j.ddmod.2011.04.001
DO - 10.1016/j.ddmod.2011.04.001
M3 - Review article
AN - SCOPUS:79958727594
SN - 1740-6757
VL - 7
SP - 123
EP - 130
JO - Drug Discovery Today: Disease Models
JF - Drug Discovery Today: Disease Models
IS - 3-4
ER -