Template-guided stereotactic implantation of malignant brain tumors for interstitial thermoradiotherapy

R. P. Lacono, B. Stea, B. A. Lulu, T. R. Cetas, J. R. Cassady

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


A phase I trial of 25 patients with anaplastic astrocytoma or glioblastoma multiforme is described. Hyperthermia and radiation were delivered siercoiactical-ly by means of template-guided interstitial catheters loaded with ferromagnetic wires and then lr seeds. Implant volumes ranged from 15 to 113 ml (mean 54 ml) involving 9-38 catheters (mean 18); parallel catheters used hexagonal spacing of 1.0-1.5 cm. Patient tolerance of these procedures was excellent. Postoperative morbidity due to additional mass effect or edema was low. hut there has been one death and one complication of hydrocephalus, bleeding and symptomatic pneumocephalus, each.

Original languageEnglish (US)
Pages (from-to)199-204
Number of pages6
JournalStereotactic and Functional Neurosurgery
Issue number1-4
StatePublished - 1992


  • Brachytherapy
  • Hyperthermia
  • Stereotactic surgery

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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