Template-guided stereotactic implantation of malignant brain tumors for interstitial thermoradiotherapy

R. P. Lacono; B. Stea; B. A. Lulu; T. R. Cetas; J. R. Cassady

doi:10.1159/000098942

Template-guided stereotactic implantation of malignant brain tumors for interstitial thermoradiotherapy

R. P. Lacono, B. Stea, B. A. Lulu, T. R. Cetas, J. R. Cassady

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A phase I trial of 25 patients with anaplastic astrocytoma or glioblastoma multiforme is described. Hyperthermia and radiation were delivered siercoiactical-ly by means of template-guided interstitial catheters loaded with ferromagnetic wires and then lr seeds. Implant volumes ranged from 15 to 113 ml (mean 54 ml) involving 9-38 catheters (mean 18); parallel catheters used hexagonal spacing of 1.0-1.5 cm. Patient tolerance of these procedures was excellent. Postoperative morbidity due to additional mass effect or edema was low. hut there has been one death and one complication of hydrocephalus, bleeding and symptomatic pneumocephalus, each.

Original language	English (US)
Pages (from-to)	199-204
Number of pages	6
Journal	Stereotactic and Functional Neurosurgery
Volume	59
Issue number	1-4
DOIs	https://doi.org/10.1159/000098942
State	Published - 1992

Keywords

Brachytherapy
Hyperthermia
Stereotactic surgery

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1159/000098942

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title = "Template-guided stereotactic implantation of malignant brain tumors for interstitial thermoradiotherapy",

abstract = "A phase I trial of 25 patients with anaplastic astrocytoma or glioblastoma multiforme is described. Hyperthermia and radiation were delivered siercoiactical-ly by means of template-guided interstitial catheters loaded with ferromagnetic wires and then lr seeds. Implant volumes ranged from 15 to 113 ml (mean 54 ml) involving 9-38 catheters (mean 18); parallel catheters used hexagonal spacing of 1.0-1.5 cm. Patient tolerance of these procedures was excellent. Postoperative morbidity due to additional mass effect or edema was low. hut there has been one death and one complication of hydrocephalus, bleeding and symptomatic pneumocephalus, each.",

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AU - Lacono, R. P.

AU - Stea, B.

AU - Lulu, B. A.

AU - Cetas, T. R.

AU - Cassady, J. R.

PY - 1992

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N2 - A phase I trial of 25 patients with anaplastic astrocytoma or glioblastoma multiforme is described. Hyperthermia and radiation were delivered siercoiactical-ly by means of template-guided interstitial catheters loaded with ferromagnetic wires and then lr seeds. Implant volumes ranged from 15 to 113 ml (mean 54 ml) involving 9-38 catheters (mean 18); parallel catheters used hexagonal spacing of 1.0-1.5 cm. Patient tolerance of these procedures was excellent. Postoperative morbidity due to additional mass effect or edema was low. hut there has been one death and one complication of hydrocephalus, bleeding and symptomatic pneumocephalus, each.

AB - A phase I trial of 25 patients with anaplastic astrocytoma or glioblastoma multiforme is described. Hyperthermia and radiation were delivered siercoiactical-ly by means of template-guided interstitial catheters loaded with ferromagnetic wires and then lr seeds. Implant volumes ranged from 15 to 113 ml (mean 54 ml) involving 9-38 catheters (mean 18); parallel catheters used hexagonal spacing of 1.0-1.5 cm. Patient tolerance of these procedures was excellent. Postoperative morbidity due to additional mass effect or edema was low. hut there has been one death and one complication of hydrocephalus, bleeding and symptomatic pneumocephalus, each.

KW - Brachytherapy

KW - Hyperthermia

KW - Stereotactic surgery

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Template-guided stereotactic implantation of malignant brain tumors for interstitial thermoradiotherapy

Abstract

Keywords

ASJC Scopus subject areas

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