Telomeres and telomerase in renal health

Lauren P. Wills, Rick G. Schnellmann

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

The role of telomeres and telomerase in human biology has been studied since the early 1990s because telomere attrition is implicated in various diseases including cardiovascular dysfunction, carcinogenesis, and the progression of acute kidney injury. Telomeric length is a reliable indicator of intrinsic biologic age and a surrogate for the mitotic clock. Because the prevalence of chronic kidney disease increases with age, telomere length and telomerase activity may play a role in its progression.

Original languageEnglish (US)
Pages (from-to)39-41
Number of pages3
JournalJournal of the American Society of Nephrology
Volume22
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

ASJC Scopus subject areas

  • Nephrology

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