Systemic treatments for noninfectious vitreous inflammation

Angela Jiang, Jillian Wang, Malav Joshi, John Byron Christoforidis

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Vitreous inflammation, or vitritis, may result from many causes, including both infectious and noninfectious, including rheumatologic and autoimmune processes. Vitritis is commonly vision threatening and has serious sequelae. Treatment is frequently challenging, but, today, there are multiple methods of systemic treatment for vitritis. These categories include corticosteroids, antimetabolites, alkylating agents, T-cell inhibitors/calcineurin inhibitors, and biologic agents. These treatment categories were reviewed last year, but, even over the course of just a year, many therapies have made progress, as we have learned more about their indications and efficacy. We discuss here discoveries made over the past year on both existing and new drugs, as well as reviewing mechanisms of action, clinical dosages, specific conditions that are treated, adverse effects, and usual course of treatment for each class of therapy.

Original languageEnglish (US)
Article number515312
JournalMediators of Inflammation
StatePublished - 2013

ASJC Scopus subject areas

  • Immunology
  • Cell Biology


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