Abstract
We report a new synthesis of the seleno-bis (S-glutathionyl) arsinium anion, [(GS)2AsSe]-. An aqueous solution of bis-glutathionylarsenous acid. (GS)2As-OH, prepared form stoichiometric glutathione and arsenite, was reacted in situ with a solution of sodium hydrogen selenide, prepared from elemental selenium and sodium borohydride. Analysis of the arsenic and selenium K-edge X-ray absorption spectra indicated virtually quantitative formation of [(GS)2AsSe]- with As Se and As-S distances of 2.31 and 2.25 Å, respectively, and the concentrated sample allowed a definitive X-ray spectroscopic characterization. Size-exclusion chromatography was used to separate [(GS)2AsSe]- from residual borate in the reaction mixture.
Original language | English (US) |
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Pages (from-to) | 108-113 |
Number of pages | 6 |
Journal | Journal of Organometallic Chemistry |
Volume | 650 |
Issue number | 1-2 |
DOIs | |
State | Published - May 1 2002 |
Externally published | Yes |
Keywords
- Arsinium anion
- S-glutathionyl
- Size-exclusion chromatography
- X-ray absorption spectroscopy
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry
- Materials Chemistry