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Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs)
Zhengnan Shen
, Kiira Ratia
, Isabella Krider
, Martha Ackerman-Berrier
, Christopher Penton
, Soumya Reddy Musku
, Jesse M. Gordon-Blake
, Megan S. Laham
, Nicholas Christie
, Nina Ma
, Jiqiang Fu
, Rui Xiong
, Jenna M. Courey
, Ganga Reddy Velma
,
Gregory R.J. Thatcher
Pharmacology and Toxicology
Research output
:
Contribution to journal
›
Article
›
peer-review
9
Scopus citations
Overview
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Dive into the research topics of 'Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs)'. Together they form a unique fingerprint.
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Medicine and Dentistry
Structure-Activity Relationship
100%
Nicotinamide Phosphoribosyltransferase
100%
Allosteric Modulator
100%
Nicotinamide Adenine Dinucleotide
66%
Nicotinamide
33%
Dietary Supplement
22%
Binding Affinity
22%
Enzyme Activation
22%
Disease
11%
Enzyme Activity
11%
Pharmacology, Toxicology and Pharmaceutical Science
Structure Activity Relationship
100%
Nicotinamide Phosphoribosyltransferase
100%
Positive Allosteric Modulator
100%
Nicotinamide Adenine Dinucleotide
66%
Nicotinamide
33%
Dietary Supplement
22%
Disease
11%
Biochemistry, Genetics and Molecular Biology
Structure Activity Relation
100%
Nicotinamide Phosphoribosyltransferase
100%
Nicotinamide Adenine Dinucleotide
66%
Nicotinamide
33%
Binding Affinity
22%
Enzyme Activation
22%
Enzyme
11%
Small Molecule
11%
Enzyme Activity
11%
Product Inhibition
11%
Keyphrases
Loss of Effectiveness
11%