Synthesis of [14C]-imexon

Bhumasamudram Jagadish; Bhashyam S. Iyengar; Anikó M. Sólyom; William A. Remers; Robert T Dorr; Jason Shin Yu; Surendra Gupta; Eugene A. Mash

doi:10.1002/jlcr.911

Synthesis of [¹⁴C]-imexon

Bhumasamudram Jagadish
, Bhashyam S. Iyengar
, Anikó M. Sólyom
, William A. Remers
, Robert T Dorr
, Jason Shin Yu
, Surendra Gupta
, Eugene A. Mash

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A four-step synthesis of [¹⁴C]-imexon is described, starting from [¹⁴C]-phosgene. The overall yield is 27% and the specific activity is 55 mCi/mmol.

Original language	English (US)
Pages (from-to)	165-170
Number of pages	6
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	48
Issue number	3
DOIs	https://doi.org/10.1002/jlcr.911
State	Published - Mar 2005

Keywords

Anticancer agent
Aziridine
Imexon
Sulfhydryl-binding

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Radiology Nuclear Medicine and imaging
Drug Discovery
Spectroscopy
Organic Chemistry

Access to Document

10.1002/jlcr.911

Cite this

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title = "Synthesis of [14C]-imexon",

abstract = "A four-step synthesis of [14C]-imexon is described, starting from [14C]-phosgene. The overall yield is 27\% and the specific activity is 55 mCi/mmol.",

keywords = "Anticancer agent, Aziridine, Imexon, Sulfhydryl-binding",

author = "Bhumasamudram Jagadish and Iyengar, \{Bhashyam S.\} and S{\'o}lyom, \{Anik{\'o} M.\} and Remers, \{William A.\} and Dorr, \{Robert T\} and Yu, \{Jason Shin\} and Surendra Gupta and Mash, \{Eugene A.\}",

year = "2005",

month = mar,

doi = "10.1002/jlcr.911",

language = "English (US)",

volume = "48",

pages = "165--170",

journal = "Journal of Labelled Compounds and Radiopharmaceuticals",

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publisher = "John Wiley and Sons Ltd",

number = "3",

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T1 - Synthesis of [14C]-imexon

AU - Jagadish, Bhumasamudram

AU - Iyengar, Bhashyam S.

AU - Sólyom, Anikó M.

AU - Remers, William A.

AU - Dorr, Robert T

AU - Yu, Jason Shin

AU - Gupta, Surendra

AU - Mash, Eugene A.

PY - 2005/3

Y1 - 2005/3

N2 - A four-step synthesis of [14C]-imexon is described, starting from [14C]-phosgene. The overall yield is 27% and the specific activity is 55 mCi/mmol.

AB - A four-step synthesis of [14C]-imexon is described, starting from [14C]-phosgene. The overall yield is 27% and the specific activity is 55 mCi/mmol.

KW - Anticancer agent

KW - Aziridine

KW - Imexon

KW - Sulfhydryl-binding

UR - https://www.scopus.com/pages/publications/16244389629

UR - https://www.scopus.com/pages/publications/16244389629#tab=citedBy

U2 - 10.1002/jlcr.911

DO - 10.1002/jlcr.911

M3 - Article

AN - SCOPUS:16244389629

SN - 0362-4803

VL - 48

SP - 165

EP - 170

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

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