Synthesis of racemic fecapentaene-12, a potent mutagen from human feces, and its regioisomer

A. A.Leslie Gunatilaka; Nobuhiro Hirai; David G.I. Kingston

doi:10.1016/S0040-4039(00)94111-X

Synthesis of racemic fecapentaene-12, a potent mutagen from human feces, and its regioisomer

A. A.Leslie Gunatilaka
, Nobuhiro Hirai
, David G.I. Kingston

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Racemic fecapentaene-12 [3-(1,3,5,7,9-dodecapentaenyloxy)-1,2-propanediol (1)] and its regioisomer 2-(1,3,5,7,9-dodecapentaenyloxy)-1,3-propanediol (2) have been synthesized. The latter compound is comparably mutagenic to 1.

Original language	English (US)
Pages (from-to)	5457-5460
Number of pages	4
Journal	Tetrahedron Letters
Volume	24
Issue number	49
DOIs	https://doi.org/10.1016/S0040-4039(00)94111-X
State	Published - 1983
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Synthesis of racemic fecapentaene-12, a potent mutagen from human feces, and its regioisomer",

abstract = "Racemic fecapentaene-12 [3-(1,3,5,7,9-dodecapentaenyloxy)-1,2-propanediol (1)] and its regioisomer 2-(1,3,5,7,9-dodecapentaenyloxy)-1,3-propanediol (2) have been synthesized. The latter compound is comparably mutagenic to 1.",

author = "Gunatilaka, \{A. A.Leslie\} and Nobuhiro Hirai and Kingston, \{David G.I.\}",

note = "Funding Information: National Cancer Institute through Grant CA-23857.",

year = "1983",

doi = "10.1016/S0040-4039(00)94111-X",

language = "English (US)",

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T1 - Synthesis of racemic fecapentaene-12, a potent mutagen from human feces, and its regioisomer

AU - Gunatilaka, A. A.Leslie

AU - Hirai, Nobuhiro

AU - Kingston, David G.I.

N1 - Funding Information: National Cancer Institute through Grant CA-23857.

PY - 1983

Y1 - 1983

N2 - Racemic fecapentaene-12 [3-(1,3,5,7,9-dodecapentaenyloxy)-1,2-propanediol (1)] and its regioisomer 2-(1,3,5,7,9-dodecapentaenyloxy)-1,3-propanediol (2) have been synthesized. The latter compound is comparably mutagenic to 1.

AB - Racemic fecapentaene-12 [3-(1,3,5,7,9-dodecapentaenyloxy)-1,2-propanediol (1)] and its regioisomer 2-(1,3,5,7,9-dodecapentaenyloxy)-1,3-propanediol (2) have been synthesized. The latter compound is comparably mutagenic to 1.

UR - https://www.scopus.com/pages/publications/2142831067

UR - https://www.scopus.com/pages/publications/2142831067#tab=citedBy

U2 - 10.1016/S0040-4039(00)94111-X

DO - 10.1016/S0040-4039(00)94111-X

M3 - Article

AN - SCOPUS:2142831067

SN - 0040-4039

VL - 24

SP - 5457

EP - 5460

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

Synthesis of racemic fecapentaene-12, a potent mutagen from human feces, and its regioisomer

Abstract

ASJC Scopus subject areas

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