Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

Hong Yu Li; Yao Ling Qiu; Elisabeth Moyroud; Yoshito Kishi

Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

Hong Yu Li, Yao Ling Qiu, Elisabeth Moyroud, Yoshito Kishi

Research output: Contribution to journal › Article › peer-review

Abstract

Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH₂-bridged base-pair model that should be conformationally flexible, even after base pairing.

Original language	English (US)
Pages (from-to)	1471-1475
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	40
Issue number	8
State	Published - Apr 17 2001
Externally published	Yes

Keywords

Nucleosides
Nucleotides
Oligonucleotides
Solid-phase synthesis
Watson-Crick base pairs

ASJC Scopus subject areas

Catalysis
General Chemistry

Cite this

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title = "Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model",

abstract = "Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH2-bridged base-pair model that should be conformationally flexible, even after base pairing.",

keywords = "Nucleosides, Nucleotides, Oligonucleotides, Solid-phase synthesis, Watson-Crick base pairs",

author = "Li, \{Hong Yu\} and Qiu, \{Yao Ling\} and Elisabeth Moyroud and Yoshito Kishi",

year = "2001",

month = apr,

day = "17",

language = "English (US)",

volume = "40",

pages = "1471--1475",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "8",

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T1 - Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

AU - Li, Hong Yu

AU - Qiu, Yao Ling

AU - Moyroud, Elisabeth

AU - Kishi, Yoshito

PY - 2001/4/17

Y1 - 2001/4/17

N2 - Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH2-bridged base-pair model that should be conformationally flexible, even after base pairing.

AB - Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH2-bridged base-pair model that should be conformationally flexible, even after base pairing.

KW - Nucleosides

KW - Nucleotides

KW - Oligonucleotides

KW - Solid-phase synthesis

KW - Watson-Crick base pairs

UR - https://www.scopus.com/pages/publications/0035901641

UR - https://www.scopus.com/inward/citedby.url?scp=0035901641&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0035901641

SN - 1433-7851

VL - 40

SP - 1471

EP - 1475

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 8

ER -

Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

Abstract

Keywords

ASJC Scopus subject areas

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