Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

Hong Yu Li; Yao Ling Qiu; Elisabeth Moyroud; Yoshito Kishi

doi:10.1002/1521-3773(20010417)40:8<1456::AID-ANIE1456>3.0.CO;2-T

Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

Hong Yu Li, Yao Ling Qiu, Elisabeth Moyroud, Yoshito Kishi

Pharmacology and Toxicology

Research output: Contribution to journal › Article › peer-review

Abstract

Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH₂-bridged base-pair model that should be conformationally flexible, even after base pairing.

Original language	English (US)
Pages (from-to)	1471-1475
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	40
Issue number	8
DOIs	https://doi.org/10.1002/1521-3773(20010417)40:8<1456::AID-ANIE1456>3.0.CO;2-T
State	Published - Apr 17 2001

Keywords

Nucleosides
Nucleotides
Oligonucleotides
Solid-phase synthesis
Watson-Crick base pairs

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/1521-3773(20010417)40:8<1456::AID-ANIE1456>3.0.CO;2-T

Cite this

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title = "Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model",

abstract = "Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH2-bridged base-pair model that should be conformationally flexible, even after base pairing.",

keywords = "Nucleosides, Nucleotides, Oligonucleotides, Solid-phase synthesis, Watson-Crick base pairs",

author = "Li, {Hong Yu} and Qiu, {Yao Ling} and Elisabeth Moyroud and Yoshito Kishi",

year = "2001",

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doi = "10.1002/1521-3773(20010417)40:8<1456::AID-ANIE1456>3.0.CO;2-T",

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AU - Li, Hong Yu

AU - Qiu, Yao Ling

AU - Moyroud, Elisabeth

AU - Kishi, Yoshito

PY - 2001/4/17

Y1 - 2001/4/17

N2 - Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH2-bridged base-pair model that should be conformationally flexible, even after base pairing.

AB - Building bridges: A feasible solidphase synthesis of antiparallel n-, h-, and H-type DNA oligomers (see picture) has been demonstrated. The oligomers possess a CH2-bridged base-pair model that should be conformationally flexible, even after base pairing.

KW - Nucleosides

KW - Nucleotides

KW - Oligonucleotides

KW - Solid-phase synthesis

KW - Watson-Crick base pairs

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

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Synthesis of DNA oligomers possessing a covalently cross-linked Watson - Crick base pair model

Abstract

Keywords

ASJC Scopus subject areas

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