Synthesis of a diverse library of N,N-dimethylamino containing monomers appropriate as lipid head groups

Ian W. Jones; Anne M. Simon; S. Scott Saavedra; H. K. Hall

doi:10.1016/j.tetlet.2011.08.042

Synthesis of a diverse library of N,N-dimethylamino containing monomers appropriate as lipid head groups

Ian W. Jones, Anne M. Simon, S. Scott Saavedra, H. K. Hall

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We report on the synthesis of a diverse library of N,N-dimethylamino containing monomers. Subjecting these monomers to Chabrier reaction conditions would yield lipids with polymerizable head groups. This library of lipid head groups is equipped with arms of various lengths containing reduction-oxidation polymerizable groups at the terminus.

Original language	English (US)
Pages (from-to)	5547-5549
Number of pages	3
Journal	Tetrahedron Letters
Volume	52
Issue number	43
DOIs	https://doi.org/10.1016/j.tetlet.2011.08.042
State	Published - Oct 26 2011

Keywords

Chabrier reaction
Lipid monomers
N,N-Dimethylamino containing monomers
Reduction-oxidation
T-Rex effect

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2011.08.042

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abstract = "We report on the synthesis of a diverse library of N,N-dimethylamino containing monomers. Subjecting these monomers to Chabrier reaction conditions would yield lipids with polymerizable head groups. This library of lipid head groups is equipped with arms of various lengths containing reduction-oxidation polymerizable groups at the terminus.",

keywords = "Chabrier reaction, Lipid monomers, N,N-Dimethylamino containing monomers, Reduction-oxidation, T-Rex effect",

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AU - Jones, Ian W.

AU - Simon, Anne M.

AU - Saavedra, S. Scott

AU - Hall, H. K.

PY - 2011/10/26

Y1 - 2011/10/26

N2 - We report on the synthesis of a diverse library of N,N-dimethylamino containing monomers. Subjecting these monomers to Chabrier reaction conditions would yield lipids with polymerizable head groups. This library of lipid head groups is equipped with arms of various lengths containing reduction-oxidation polymerizable groups at the terminus.

AB - We report on the synthesis of a diverse library of N,N-dimethylamino containing monomers. Subjecting these monomers to Chabrier reaction conditions would yield lipids with polymerizable head groups. This library of lipid head groups is equipped with arms of various lengths containing reduction-oxidation polymerizable groups at the terminus.

KW - Chabrier reaction

KW - Lipid monomers

KW - N,N-Dimethylamino containing monomers

KW - Reduction-oxidation

KW - T-Rex effect

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

Synthesis of a diverse library of N,N-dimethylamino containing monomers appropriate as lipid head groups

Abstract

Keywords

ASJC Scopus subject areas

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