Synthesis of 3-substituted 1,5-aldehyde esters via an organocatalytic highly enantioselective conjugate addition of new carbonylmethyl 2-pyridinylsulfone to enals

Jing Deng; Fei Wang; Wenzhong Yan; Jin Zhu; Hualiang Jiang; Wei Wang; Jian Li

doi:10.1039/c1cc15714k

Synthesis of 3-substituted 1,5-aldehyde esters via an organocatalytic highly enantioselective conjugate addition of new carbonylmethyl 2-pyridinylsulfone to enals

Jing Deng, Fei Wang, Wenzhong Yan, Jin Zhu, Hualiang Jiang, Wei Wang, Jian Li

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A highly enantioselective organocatalytic protocol for conjugate addition of new nucleophilic carbonylmethyl 2-pyridinylsulfone to enals has been developed in good yields and with high enantioselectivities. The resulting Michael adducts are versatile building blocks for a variety of organic transformations.

Original language	English (US)
Pages (from-to)	148-150
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	1
DOIs	https://doi.org/10.1039/c1cc15714k
State	Published - Nov 28 2012
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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abstract = "A highly enantioselective organocatalytic protocol for conjugate addition of new nucleophilic carbonylmethyl 2-pyridinylsulfone to enals has been developed in good yields and with high enantioselectivities. The resulting Michael adducts are versatile building blocks for a variety of organic transformations.",

author = "Jing Deng and Fei Wang and Wenzhong Yan and Jin Zhu and Hualiang Jiang and Wei Wang and Jian Li",

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T1 - Synthesis of 3-substituted 1,5-aldehyde esters via an organocatalytic highly enantioselective conjugate addition of new carbonylmethyl 2-pyridinylsulfone to enals

AU - Deng, Jing

AU - Wang, Fei

AU - Yan, Wenzhong

AU - Zhu, Jin

AU - Jiang, Hualiang

AU - Wang, Wei

AU - Li, Jian

PY - 2012/11/28

Y1 - 2012/11/28

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AB - A highly enantioselective organocatalytic protocol for conjugate addition of new nucleophilic carbonylmethyl 2-pyridinylsulfone to enals has been developed in good yields and with high enantioselectivities. The resulting Michael adducts are versatile building blocks for a variety of organic transformations.

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Synthesis of 3-substituted 1,5-aldehyde esters via an organocatalytic highly enantioselective conjugate addition of new carbonylmethyl 2-pyridinylsulfone to enals

Abstract

ASJC Scopus subject areas

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