TY - JOUR
T1 - Synthesis and structures of Zn(C6H12OS2)2(ClO 4)2 and Zn(C3H6NS2)2(C3 H4N2)- Model compounds for the Zn sites in RNA polymerase
AU - Chen, Dong
AU - Powers, Linda
N1 - Funding Information:
We thank Dr. J. L. Hubbard, of the Department of Chemistry and Biochemistry, Utah State University, for his help with the single crystal structures. The X-ray diffractometer was purchased with equal funding from the Natural Science Foundation (CHE-9002379) and the Utah State University Research Office.
PY - 1995/6
Y1 - 1995/6
N2 - Model compounds for the Zn sites of the β′ and the β subunits in RNA polymerase [1] were synthesized. Single crystal structures and X-ray absorption spectroscopy measurements for these two model complexes are reported. In Zn(C6H12OS2)2(ClO 4)2, the Zn is coordinated by four sulfur and two oxygen atoms. The average ZnS bond length is 2.514 Å and the ZnO bond length is 2.089 Å, which are similar to these bond distances reported for the Zn site in the β′ subunit of RNA polymerase. In Zn(C3H6NS2)2(C3 H4N2), the Zn atom is coordinated by four sulfur atoms and one nitrogen atom of an imidazole group. The average of the ZnS bond length is 2.469 Å and the ZnN bond length is 2.009 Å, which are also similar to the ZnS and ZnN bonds in the β subunits of RNA polymerase.
AB - Model compounds for the Zn sites of the β′ and the β subunits in RNA polymerase [1] were synthesized. Single crystal structures and X-ray absorption spectroscopy measurements for these two model complexes are reported. In Zn(C6H12OS2)2(ClO 4)2, the Zn is coordinated by four sulfur and two oxygen atoms. The average ZnS bond length is 2.514 Å and the ZnO bond length is 2.089 Å, which are similar to these bond distances reported for the Zn site in the β′ subunit of RNA polymerase. In Zn(C3H6NS2)2(C3 H4N2), the Zn atom is coordinated by four sulfur atoms and one nitrogen atom of an imidazole group. The average of the ZnS bond length is 2.469 Å and the ZnN bond length is 2.009 Å, which are also similar to the ZnS and ZnN bonds in the β subunits of RNA polymerase.
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U2 - 10.1016/0162-0134(94)00058-I
DO - 10.1016/0162-0134(94)00058-I
M3 - Article
C2 - 7500087
AN - SCOPUS:0029030999
SN - 0162-0134
VL - 58
SP - 245
EP - 253
JO - Journal of Inorganic Biochemistry
JF - Journal of Inorganic Biochemistry
IS - 4
ER -