Abstract
The cytotoxic sterols 1 and 2, previously isolated from Pseudobersama mossambicenis, have been synthesized in nine steps from stigmasterol, together with seven related sterols. Structure-activity relationships of these sterols in cytotoxicity and DNA-damaging assays are discussed.
Original language | English (US) |
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Pages (from-to) | 620-628 |
Number of pages | 9 |
Journal | Journal Of Natural Products |
Volume | 57 |
Issue number | 5 |
DOIs | |
State | Published - May 1 1994 |
ASJC Scopus subject areas
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry