Synthesis and Structure-Activity Relationships of 5′-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δOpioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects

Rakesh H. Vekariya, Wei Lei, Abhisek Ray, Surendra K. Saini, Sixue Zhang, Gabriella Molnar, Deborah Barlow, Kelly L. Karlage, Edward J. Bilsky, Karen L. Houseknecht, Tally M. Largent-Milnes, John M. Streicher, Subramaniam Ananthan

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Pharmacology, Toxicology and Pharmaceutical Science

Neuroscience