We present a modular synthesis of a new class of chiral N,N-chelating ligands containing the C2-symmetric trans-2,5-disubstituted pyrrolidine moiety linked to a pyridine ring. (-)-2-[(2R,5R)-2,5-Dimethylpyrrolidin-1-ylmethyl]pyridine (11, (R,R)-MePMP), (-)-2-[2((2R,5R)-2,5-dimethylpyrrolidin- (12, (R,R)-MePEP), and (+)-2-[(2R,5R)-2,5-diphenylpyrrolidin-1-ylmethyl]pyridine (13, (R,R)-PhPMP) have been prepared. The X-ray structure of the (Λ3-allyl)Pd complex of (R,R)-MePMP (11) is reported.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry