TY - JOUR
T1 - Synthesis and characterization of new amine-imine ligands based on trans-2,5-disubstituted pyrrolidines
AU - Sweet, James A.
AU - Cavallari, Jennifer M.
AU - Price, William A.
AU - Ziller, Joseph W.
AU - McGrath, Dominic V.
N1 - Funding Information:
We are grateful to Per-Ola Norrby and Mark Burk for helpful discussions. Acknowledgement is made to the donors of The Petroleum Research Fund, administered by the ACS, and the University of Connecticut Research Foundation for support of this research. J.M.C. was the recipient of a Pfizer Summer Undergraduate Research Fellowship, for which she is grateful.
PY - 1997/1/23
Y1 - 1997/1/23
N2 - We present a modular synthesis of a new class of chiral N,N-chelating ligands containing the C2-symmetric trans-2,5-disubstituted pyrrolidine moiety linked to a pyridine ring. (-)-2-[(2R,5R)-2,5-Dimethylpyrrolidin-1-ylmethyl]pyridine (11, (R,R)-MePMP), (-)-2-[2((2R,5R)-2,5-dimethylpyrrolidin- (12, (R,R)-MePEP), and (+)-2-[(2R,5R)-2,5-diphenylpyrrolidin-1-ylmethyl]pyridine (13, (R,R)-PhPMP) have been prepared. The X-ray structure of the (Λ3-allyl)Pd complex of (R,R)-MePMP (11) is reported.
AB - We present a modular synthesis of a new class of chiral N,N-chelating ligands containing the C2-symmetric trans-2,5-disubstituted pyrrolidine moiety linked to a pyridine ring. (-)-2-[(2R,5R)-2,5-Dimethylpyrrolidin-1-ylmethyl]pyridine (11, (R,R)-MePMP), (-)-2-[2((2R,5R)-2,5-dimethylpyrrolidin- (12, (R,R)-MePEP), and (+)-2-[(2R,5R)-2,5-diphenylpyrrolidin-1-ylmethyl]pyridine (13, (R,R)-PhPMP) have been prepared. The X-ray structure of the (Λ3-allyl)Pd complex of (R,R)-MePMP (11) is reported.
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U2 - 10.1016/S0957-4166(96)00511-3
DO - 10.1016/S0957-4166(96)00511-3
M3 - Article
AN - SCOPUS:0031036227
SN - 0957-4166
VL - 8
SP - 207
EP - 211
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
IS - 2
ER -