Abstract
195 genes coding for proteins in four different folding types have been analyzed in terms of variance analysis, in which there are 50 genes coding for all alpha proteins, 66 entries for all beta proteins, 37 entries for alpha+beta proteins and 42 entries for alpha/beta proteins. We have observed that codon usage in different gene classes coding for differently folded proteins is significantly different. Similar to amino acid propensities in different protein classes, folding type specific proteins have specific codon usage patterns. With the help of codon usage pattern, we can improve the accuracy of prediction of protein folding type and further prediction of protein secondary structure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2202-2203 |
| Number of pages | 2 |
| Journal | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Volume | 3 |
| State | Published - 2002 |
| Externally published | Yes |
| Event | Proceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States Duration: Oct 23 2002 → Oct 26 2002 |
Keywords
- Protein folding type
- Protein secondary structure prediction
- Synonymous codon usage
- Variance analysis
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics