Susceptible mice: Identifying a diabetic nephropathy disease locus using a murine model

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7 Scopus citations

Abstract

Diabetic nephropathy is a common, complex disease with a clear genetic predisposition. Human gene association studies are beginning to bear fruit by identifying gene loci that increase diabetic nephropathy risk. Chua et al. report a similar study in diabetic mice that reveals a major nephropathy locus on chromosome 8. Could this be a human nephropathy gene? Time will tell, but such findings will at least improve the use of mouse models of human kidney disease.

Original languageEnglish (US)
Pages (from-to)431-432
Number of pages2
JournalKidney International
Volume78
Issue number5
DOIs
StatePublished - Sep 2010
Externally publishedYes

ASJC Scopus subject areas

  • Nephrology

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