Surgical probe design for a coincidence imaging system without a collimator

J. R. Saffer; H. H. Barrett; H. B. Barber; J. M. Woolfenden

doi:10.1007/BFb0033738

Surgical probe design for a coincidence imaging system without a collimator

J. R. Saffer, H. H. Barrett, H. B. Barber, J. M. Woolfenden

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Surgical probes used in nuclear medicine can be maneuvered close to a suspected tumor site, thereby achieving higher resolution and sensitivity than external gamma cameras. Tomography with handheld probes is not possible, however, so it is difficult to determine whether an increase in the photon count rate is caused by features near the probe or by variations in the distant background radiation. Our group has experimented with several probe designs that address this problem. This paper describes a probe that images nearby objects without a collimator and is insensitive to inhomogeneities in the distant background level. The probe, which is used with a radionuclide that emits multiple photons per decay, such as 111In, consists of a collimatorless array of gamma-ray detectors connected by coincidence circuitry. We used a Monte Carlo routine to simulate data collection from such a system and reconstructed the images using the pseudoinverse obtained by singular value decomposition (SVD). The images show a significant suppression of distant sources when compared to a probe equipped with a conventional parallel-hole collimator.

Original language	English (US)
Title of host publication	Information Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings
Editors	Alan C.F. Colchester, David J. Hawkes
Publisher	Springer-Verlag
Pages	9-22
Number of pages	14
ISBN (Print)	9783540542469
DOIs	https://doi.org/10.1007/BFb0033738
State	Published - 1991
Externally published	Yes
Event	12th International Conference on Information Processing in Medical Imaging, IPMI 1991 - Wye, United Kingdom Duration: Jul 7 1991 → Jul 12 1991

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	511 LNCS
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Other

Other	12th International Conference on Information Processing in Medical Imaging, IPMI 1991
Country/Territory	United Kingdom
City	Wye
Period	7/7/91 → 7/12/91

Keywords

Gamma rays
Monte carlo
Nuclear medicine
Singular value decomposition (SVD)
Surgical probes

ASJC Scopus subject areas

Theoretical Computer Science
General Computer Science

Access to Document

10.1007/BFb0033738

Cite this

Saffer, J. R., Barrett, H. H., Barber, H. B., & Woolfenden, J. M. (1991). Surgical probe design for a coincidence imaging system without a collimator. In A. C. F. Colchester, & D. J. Hawkes (Eds.), Information Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings (pp. 9-22). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 511 LNCS). Springer-Verlag. https://doi.org/10.1007/BFb0033738

Surgical probe design for a coincidence imaging system without a collimator. / Saffer, J. R.; Barrett, H. H.; Barber, H. B. et al.
Information Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings. ed. / Alan C.F. Colchester; David J. Hawkes. Springer-Verlag, 1991. p. 9-22 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 511 LNCS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Saffer, JR, Barrett, HH, Barber, HB & Woolfenden, JM 1991, Surgical probe design for a coincidence imaging system without a collimator. in ACF Colchester & DJ Hawkes (eds), Information Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 511 LNCS, Springer-Verlag, pp. 9-22, 12th International Conference on Information Processing in Medical Imaging, IPMI 1991, Wye, United Kingdom, 7/7/91. https://doi.org/10.1007/BFb0033738

Saffer JR, Barrett HH, Barber HB, Woolfenden JM. Surgical probe design for a coincidence imaging system without a collimator. In Colchester ACF, Hawkes DJ, editors, Information Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings. Springer-Verlag. 1991. p. 9-22. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). doi: 10.1007/BFb0033738

Saffer, J. R. ; Barrett, H. H. ; Barber, H. B. et al. / Surgical probe design for a coincidence imaging system without a collimator. Information Processing in Medical Imaging - 12th International Conference, IPMI 1991, Proceedings. editor / Alan C.F. Colchester ; David J. Hawkes. Springer-Verlag, 1991. pp. 9-22 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

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author = "Saffer, {J. R.} and Barrett, {H. H.} and Barber, {H. B.} and Woolfenden, {J. M.}",

note = "Funding Information: We thank Ted Bawen for discussions and helpful advice. National Cancer Institute grants P01 CA23417 and R01 CA52643. Publisher Copyright: {\textcopyright} 1991, Springer Verlag. All rights reserved.; 12th International Conference on Information Processing in Medical Imaging, IPMI 1991 ; Conference date: 07-07-1991 Through 12-07-1991",

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AB - Surgical probes used in nuclear medicine can be maneuvered close to a suspected tumor site, thereby achieving higher resolution and sensitivity than external gamma cameras. Tomography with handheld probes is not possible, however, so it is difficult to determine whether an increase in the photon count rate is caused by features near the probe or by variations in the distant background radiation. Our group has experimented with several probe designs that address this problem. This paper describes a probe that images nearby objects without a collimator and is insensitive to inhomogeneities in the distant background level. The probe, which is used with a radionuclide that emits multiple photons per decay, such as 111In, consists of a collimatorless array of gamma-ray detectors connected by coincidence circuitry. We used a Monte Carlo routine to simulate data collection from such a system and reconstructed the images using the pseudoinverse obtained by singular value decomposition (SVD). The images show a significant suppression of distant sources when compared to a probe equipped with a conventional parallel-hole collimator.

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Surgical probe design for a coincidence imaging system without a collimator

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