Study on interaction between Duodenase - Protease with dual specificity and inhibitors of Bowman-Birk family

Inna P. Gladysheva, Natalia A. Popykina, Tatyana S. Zamolodchikova, Natalia I. Larionova

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The interaction between duodenase and inhibitors of Bowman-Birk type from soybeans (BBI) and lima beans (LBI) was investigated. Duodenase was shown to interact only with antichymotrypsin site of these inhibitors. The inhibition constants of duodenase by BBI, LBI, BBI-trypsin and LBI trypsin complexes were 4, 23,400, 600 nM respectively.

Original languageEnglish (US)
Pages (from-to)139-144
Number of pages6
JournalProtein and Peptide Letters
Volume9
Issue number2
DOIs
StatePublished - 2002
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Biochemistry

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