Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M^pro and cathepsin L

Search results

• Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW243

  Sacco, M. D. (Contributor), Ma, C. (Contributor), Lagarias, P. (Contributor), Gao, A. (Contributor), Townsend, J. A. (Contributor), Meng, X. (Contributor), Dube, P. (Contributor), Zhang, X. (Contributor), Hu, Y. (Contributor), Kitamura, N. (Contributor), Hurst, B. (Contributor), Tarbet, B. (Contributor), Marty, M. T. (Contributor), Kolocouris, A. (Contributor), Xiang, Y. (Contributor), Chen, Y. (Contributor) & Wang, J. (Contributor), Protein Data Bank (PDB), Jun 24 2020

  DOI: 10.2210/pdb6XFN/pdb, https://www.wwpdb.org/pdb?id=pdb_00006xfn

  Dataset

• Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW247

  Sacco, M. D. (Contributor), Ma, C. (Contributor), Lagarias, P. (Contributor), Gao, A. (Contributor), Townsend, J. A. (Contributor), Meng, X. (Contributor), Dube, P. (Contributor), Zhang, X. (Contributor), Hu, Y. (Contributor), Kitamura, N. (Contributor), Hurst, B. (Contributor), Tarbet, B. (Contributor), Marty, M. T. (Contributor), Kolocouris, A. (Contributor), Xiang, Y. (Contributor), Chen, Y. (Contributor) & Wang, J. (Contributor), Protein Data Bank (PDB), Jun 17 2020

  DOI: 10.2210/pdb6XBH/pdb, https://www.wwpdb.org/pdb?id=pdb_00006xbh

  Dataset

• Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248

  Sacco, M. D. (Contributor), Ma, C. (Contributor), Lagarias, P. (Contributor), Gao, A. (Contributor), Townsend, J. A. (Contributor), Meng, X. (Contributor), Dube, P. (Contributor), Zhang, X. (Contributor), Hu, Y. (Contributor), Kitamura, N. (Contributor), Hurst, B. (Contributor), Tarbet, B. (Contributor), Marty, M. T. (Contributor), Kolocouris, A. (Contributor), Xiang, Y. (Contributor), Chen, Y. (Contributor) & Wang, J. (Contributor), Protein Data Bank (PDB), Jun 17 2020

  DOI: 10.2210/pdb6XBI/pdb, https://www.wwpdb.org/pdb?id=pdb_00006xbi

  Dataset

• Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW246

  Sacco, M. D. (Contributor), Ma, C. (Contributor), Lagarias, P. (Contributor), Gao, A. (Contributor), Townsend, J. A. (Contributor), Meng, X. (Contributor), Dube, P. (Contributor), Zhang, X. (Contributor), Hu, Y. (Contributor), Kitamura, N. (Contributor), Hurst, B. (Contributor), Tarbet, B. (Contributor), Marty, M. T. (Contributor), Kolocouris, A. (Contributor), Xiang, Y. (Contributor), Chen, Y. (Contributor) & Wang, J. (Contributor), Protein Data Bank (PDB), Jun 17 2020

  DOI: 10.2210/pdb6XBG/pdb, https://www.wwpdb.org/pdb?id=pdb_00006xbg

  Dataset

• Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW241

  Sacco, M. D. (Contributor), Ma, C. (Contributor), Lagarias, P. (Contributor), Gao, A. (Contributor), Townsend, J. A. (Contributor), Meng, X. (Contributor), Dube, P. (Contributor), Zhang, X. (Contributor), Hu, Y. (Contributor), Kitamura, N. (Contributor), Hurst, B. (Contributor), Tarbet, B. (Contributor), Marty, M. T. (Contributor), Kolocouris, A. (Contributor), Xiang, Y. (Contributor), Chen, Y. (Contributor) & Wang, J. (Contributor), Protein Data Bank (PDB), Jun 17 2020

  DOI: 10.2210/pdb6XA4/pdb, https://www.wwpdb.org/pdb?id=pdb_00006xa4

  Dataset