Stress response pathways in cancer: From molecular targets to novel therapeutics

Research output: Book/ReportBook

1 Scopus citations


It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future. Coauthored by recognized leaders in cancer research from five continents, this novel book provides a comprehensive perspective on cell stress response pathways and therapeutic opportunities. Focusing on the role of genotoxic, proteotoxic, oxidative, metabolic, and inflammatory stress in tumorigenesis, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in cancer and therapeutic development.

Original languageEnglish (US)
PublisherSpringer Netherlands
Number of pages446
ISBN (Electronic)9789401794213
ISBN (Print)9789401794206
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology


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