@inbook{93f8d3ff0b634db29bbe1f258143c75e,
title = "Stress granules and ALS: A case of causation or correlation?",
abstract = "Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. These aggregates are linked to ALS pathogenesis. Recent evidence has suggested that stress granules may aid the formation of ALS protein aggregates. Here, we summarize current understanding of stress granules, focusing on assembly and clearance. We also assess the evidence linking alterations in stress granule formation and dynamics to ALS protein aggregates and disease pathology.",
keywords = "ALS, Autophagy, C9ORF72, Chaperones, Cytoskeleton, FUS, SOD1, Stress granules, TDP-43, mRNA",
author = "Nikita Fernandes and Nichole Eshleman and Buchan, {John R}",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing AG, part of Springer Nature 2018.",
year = "2018",
doi = "10.1007/978-3-319-89689-2_7",
language = "English (US)",
series = "Advances in Neurobiology",
publisher = "Springer New York LLC",
pages = "173--212",
booktitle = "Advances in Neurobiology",
}