TY - JOUR
T1 - Stereotactic fine-needle aspiration cytology of nonpalpable breast lesions
T2 - An analysis of 258 consecutive aspirates
AU - Sarfati, Mark R.
AU - Fox, Kenneth A.
AU - Warneke, James A.
AU - Fajardo, Laurie L.
AU - Hunter, Glenn C.
AU - Rappaport, William D.
PY - 1994
Y1 - 1994
N2 - background: The role of stereotactic fine-needle aspiration cytology (SFNAC) in the diagnosis of nonpalpable breast lesions is poorly defined. patients and methods: Data were prospectively collected from 225 consecutive patients with nonpalpable breast lesions who had aspiration cytology followed by immediate surgical excision. results: Between 1988 and 1993, 258 such procedures were performed. The results of 84 (33%) were interpreted as benign, 84 (33%) as atypical, 28 (11%) as suspicious for malignancy, and 49 (19%) as malignant. In all, 88 (34%) surgical specimens were malignant. SFNAC had an 80% sensitivity, a 96% specificity, a 91% positive predictive value, and an 89% negative predictive value. There were 18 false-negative and 7 false-positive aspirates. conclusions: SFNAC for diagnosing nonpalpable breast lesions is moderately sensitive and highly specific, and has a high positive and negative predictive value. In conjunction with mammography and clinical assessment, the procedure is useful for determining which patients with nonpalpable breast lesions may require surgical biopsy.
AB - background: The role of stereotactic fine-needle aspiration cytology (SFNAC) in the diagnosis of nonpalpable breast lesions is poorly defined. patients and methods: Data were prospectively collected from 225 consecutive patients with nonpalpable breast lesions who had aspiration cytology followed by immediate surgical excision. results: Between 1988 and 1993, 258 such procedures were performed. The results of 84 (33%) were interpreted as benign, 84 (33%) as atypical, 28 (11%) as suspicious for malignancy, and 49 (19%) as malignant. In all, 88 (34%) surgical specimens were malignant. SFNAC had an 80% sensitivity, a 96% specificity, a 91% positive predictive value, and an 89% negative predictive value. There were 18 false-negative and 7 false-positive aspirates. conclusions: SFNAC for diagnosing nonpalpable breast lesions is moderately sensitive and highly specific, and has a high positive and negative predictive value. In conjunction with mammography and clinical assessment, the procedure is useful for determining which patients with nonpalpable breast lesions may require surgical biopsy.
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U2 - 10.1016/S0002-9610(05)80116-3
DO - 10.1016/S0002-9610(05)80116-3
M3 - Article
C2 - 7977990
AN - SCOPUS:0027945282
SN - 0002-9610
VL - 168
SP - 529
EP - 532
JO - The American Journal of Surgery
JF - The American Journal of Surgery
IS - 6
ER -