Stereoselective reduction of α-alkoxy-β-keto esters. synthesis of (±)-trachelanthic acid and (±)-viridifloric acid

Richard S. Glass, Michael Shanklin

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Reduction of the isopropylidene derivative of A-hydroxy-A-isopropyl-B-keto-butyric acid 2b with potassium tri(sec.-butyl)-borohydride and zinc borohydride followed by hydrolysis stereoselectivity produces (±) trachelanthic acid, 3, and (±)-viridifloric acid, 4, respectively.

Original languageEnglish (US)
Pages (from-to)545-552
Number of pages8
JournalSynthetic Communications
Volume13
Issue number7
DOIs
StatePublished - May 1 1983

ASJC Scopus subject areas

  • Organic Chemistry

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