Stereocontrolled manipulations of chromatographically resolved pyranosides

Diastereoisomeric pyranoside acetals derived from enantiomerically pure α-hydroxy esters are readily separated by simple column chromatography. The "resolved" chirality center at the anomeric carbon can be used as a control element in synthetic manipulations of the pyranoside ring. 1. Introduction 2. Prior Art - Racemic Dihydropyranosides 3. Chromatographic Resolutions of Diastereoisomeric Pyranosides and Furanosides 4. Sterically Controlled Manipulations of Resolved Pyranosides 5. Chelation Controlled Manipulations of Resolved Pyranosides 5.1 Synthesis of (R)-(-)-Mevalonolactone 5.2 Synthesis of a Mevinic Acid Lactone Precursor 5.3 Approaches to the 4-Ethylamino Sugar of Calicheamicin γ _1α ¹ 6. Conclusion.