Abstract
Recent work on the development of liposomal magnetic resonance (MR) contrast agents has yielded structures with higher overall relaxivity than that of other nanoparti‐cles of similar diameter. Liposomes incorporating membrane‐bound complexes of manganese (“memsomes”) produce greater hepatic enhancement per micromole of metal ion than either ferrite particles or paramagnetic chelates. Memsomes also hold promise for targeting of sites outside the liver. Work is in progress to take these agents into clinical trials.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 195-198 |
| Number of pages | 4 |
| Journal | Journal of Magnetic Resonance Imaging |
| Volume | 3 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1993 |
| Externally published | Yes |
Keywords
- Contrast enhancemen
- Liver, MR, 761.1214
- Manganese
- iposomes
- ontrast medi
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging