Abstract
In experiments studying the effects of environmental stimuli on biological organisms, major endpoints of interest include damage to genetic components such as deoxyribonucleic acid (DNA). DNA damage as represented by mutagenic insult(s) is perhaps the most varied of any toxicological endpoint, since the potential mechanisms of genetic damage are so numerous.
| Original language | English (US) |
|---|---|
| Title of host publication | Encyclopedia of Quantitative Risk Analysis and Assessment |
| Subtitle of host publication | Melnick/Risk |
| Publisher | Wiley |
| Pages | 1-6 |
| Number of pages | 6 |
| ISBN (Electronic) | 9780470061596 |
| ISBN (Print) | 9780470035498 |
| DOIs | |
| State | Published - Jan 1 2008 |
Keywords
- downturn in dose–response
- environmental toxicity
- genetic risk assessment
- genotoxicology
- Salmonella assay
- trend testing
ASJC Scopus subject areas
- General Mathematics