Spatially selective T2 and T2* measurement with line-scan echo-planar spectroscopic imaging

Nan Kuei Chen, Koichi Oshio, Lawrence P. Panych, Frank J. Rybicki, Robert V. Mulkern

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Line-scan echo planar spectroscopic imaging (LSEPSI) is applied to quickly measure the T2 and T2* relaxation time constants in pre-selected 2D or 3D regions. Results from brain imaging studies at 3 T suggest that the proposed method may prove valuable for both basic research (e.g., quantifying the changes of T2/T2* values in functional MRI with blood oxygenation level-dependent contrast) and clinical studies (e.g., measuring the T2′ shortening due to iron deposition). The proposed spatially selective T2 and T2* mapping technique is especially well suited for studies, where T2/T2* quantification needs to be performed dynamically in a pre-selected 2D or 3D region.

Original languageEnglish (US)
Pages (from-to)90-96
Number of pages7
JournalJournal of Magnetic Resonance
Issue number1
StatePublished - Nov 2004
Externally publishedYes


  • Echo-planar spectroscopic imaging
  • Line-scan
  • T2 mapping
  • fMRI

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Nuclear and High Energy Physics
  • Condensed Matter Physics

Cite this