Abstract
The purpose of this work was to derive an equation for the rapid estimation of octanol solubilities of organic compounds. Solubilities ranging over 4 orders of magnitude were predicted with an average absolute error of 0.39 logarithmic units using melting point alone. The greatest error in prediction occurred for strongly bonded compounds.
Original language | English (US) |
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Journal | AAPS PharmSciTech |
Volume | 7 |
Issue number | 1 |
State | Published - 2006 |
ASJC Scopus subject areas
- Molecular Medicine
- Pharmaceutical Science