Sleep in Women with Chronic Pain and Autoimmune Conditions: A Narrative Review

Joan L. Shaver, Stella Iacovides

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Chronic pain and sleep disturbances are intricately intertwined. This narrative review provides comments on observations related to pain, stress-immunity, and sleep. Sleep evidence is reviewed from studies of select conditions involving pain (ie, functional somatic syndromes and autoimmune) that are predominant in women. Chronic pain and poor sleep encompass persistent stress-immune activation with systemic inflammation, cellular oxidative stress, and sick behavior indicators that increase morbidity and threaten quality of life. In painful conditions, sleep impairments are nearly ubiquitous, and exaggerated combined effects should not be underestimated or ignored, nor should crucial implications for clinical practice and research.

Original languageEnglish (US)
Pages (from-to)375-394
Number of pages20
JournalSleep Medicine Clinics
Issue number3
StatePublished - Sep 2018


  • Autoimmune
  • Chronic pain
  • PSG sleep
  • Pain sensitivity
  • Sleep quality
  • Stress-immune
  • Women

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health


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