TY - JOUR
T1 - Sleep characteristics in type 1 diabetes and associations with glycemic control
T2 - systematic review and meta-analysis
AU - Reutrakul, Sirimon
AU - Thakkinstian, Ammarin
AU - Anothaisintawee, Thunyarat
AU - Chontong, Sasipas
AU - Borel, Anne Laure
AU - Perfect, Michelle M.
AU - Janovsky, Carolina Castro Porto Silva
AU - Kessler, Romain
AU - Schultes, Bernd
AU - Harsch, Igor Alexander
AU - van Dijk, Marieke
AU - Bouhassira, Didier
AU - Matejko, Bartlomiej
AU - Lipton, Rebecca B.
AU - Suwannalai, Parawee
AU - Chirakalwasan, Naricha
AU - Schober, Anne Katrin
AU - Knutson, Kristen L.
N1 - Publisher Copyright:
© 2016 The Author(s)
PY - 2016/7/1
Y1 - 2016/7/1
N2 - Objectives The association between inadequate sleep and type 2 diabetes has garnered much attention, but little is known about sleep and type 1 diabetes (T1D). Our objectives were to conduct a systematic review and meta-analysis comparing sleep in persons with and without T1D, and to explore relationships between sleep and glycemic control in T1D. Methods Studies were identified from Medline and Scopus. Studies reporting measures of sleep in T1D patients and controls, and/or associations between sleep and glycemic control, were selected. Results A total of 22 studies were eligible for the meta-analysis. Children with T1D had shorter sleep duration (mean difference [MD] = −26.4 minutes; 95% confidence interval [CI] = −35.4, −17.7) than controls. Adults with T1D reported poorer sleep quality (MD in standardized sleep quality score = 0.51; 95% CI = 0.33, 0.70), with higher scores reflecting worse sleep quality) than controls, but there was no difference in self-reported sleep duration. Adults with TID who reported sleeping >6 hours had lower hemoglobin A1c (HbA1c) levels than those sleeping ≤6 hours (MD = −0.24%; 95% CI = −0.47, −0.02), and participants reporting good sleep quality had lower HbA1c than those with poor sleep quality (MD = −0.19%; 95% CI = −0.30, −0.08). The estimated prevalence of obstructive sleep apnea (OSA) in adults with TID was 51.9% (95% CI = 31.2, 72.6). Patients with moderate-to-severe OSA had a trend toward higher HbA1c (MD = 0.39%, 95% CI = −0.08, 0.87). Conclusion T1D was associated with poorer sleep and high prevalence of OSA. Poor sleep quality, shorter sleep duration, and OSA were associated with suboptimal glycemic control in T1D patients.
AB - Objectives The association between inadequate sleep and type 2 diabetes has garnered much attention, but little is known about sleep and type 1 diabetes (T1D). Our objectives were to conduct a systematic review and meta-analysis comparing sleep in persons with and without T1D, and to explore relationships between sleep and glycemic control in T1D. Methods Studies were identified from Medline and Scopus. Studies reporting measures of sleep in T1D patients and controls, and/or associations between sleep and glycemic control, were selected. Results A total of 22 studies were eligible for the meta-analysis. Children with T1D had shorter sleep duration (mean difference [MD] = −26.4 minutes; 95% confidence interval [CI] = −35.4, −17.7) than controls. Adults with T1D reported poorer sleep quality (MD in standardized sleep quality score = 0.51; 95% CI = 0.33, 0.70), with higher scores reflecting worse sleep quality) than controls, but there was no difference in self-reported sleep duration. Adults with TID who reported sleeping >6 hours had lower hemoglobin A1c (HbA1c) levels than those sleeping ≤6 hours (MD = −0.24%; 95% CI = −0.47, −0.02), and participants reporting good sleep quality had lower HbA1c than those with poor sleep quality (MD = −0.19%; 95% CI = −0.30, −0.08). The estimated prevalence of obstructive sleep apnea (OSA) in adults with TID was 51.9% (95% CI = 31.2, 72.6). Patients with moderate-to-severe OSA had a trend toward higher HbA1c (MD = 0.39%, 95% CI = −0.08, 0.87). Conclusion T1D was associated with poorer sleep and high prevalence of OSA. Poor sleep quality, shorter sleep duration, and OSA were associated with suboptimal glycemic control in T1D patients.
KW - Glycemic control
KW - Meta-analysis
KW - Obstructive sleep apnea
KW - Sleep duration
KW - Sleep quality
KW - Type 1 diabetes
UR - http://www.scopus.com/inward/record.url?scp=84983537874&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84983537874&partnerID=8YFLogxK
U2 - 10.1016/j.sleep.2016.03.019
DO - 10.1016/j.sleep.2016.03.019
M3 - Article
C2 - 27692274
AN - SCOPUS:84983537874
SN - 1389-9457
VL - 23
SP - 26
EP - 45
JO - Sleep Medicine
JF - Sleep Medicine
ER -