TY - JOUR
T1 - Single-Agent Therapy for Hodgkin's Disease
AU - Carter, Stephen K.
AU - Livingston, Robert B.
PY - 1973/3
Y1 - 1973/3
N2 - We have reviewed existing data on single drugs in the chemotherapy of Hodgkin's disease in order to place in perspective the recent results with regimens employing combinations of drugs. Combination chemotherapy, by historical comparison with single-drug therapy, is clearly superior in the induction of complete remission of disease. However, many single agents, particularly those in the antimetabolite and antibiotic classes of antitumor drugs, have been evaluated only minimally and may yet play important roles in the design of future combination therapies.
AB - We have reviewed existing data on single drugs in the chemotherapy of Hodgkin's disease in order to place in perspective the recent results with regimens employing combinations of drugs. Combination chemotherapy, by historical comparison with single-drug therapy, is clearly superior in the induction of complete remission of disease. However, many single agents, particularly those in the antimetabolite and antibiotic classes of antitumor drugs, have been evaluated only minimally and may yet play important roles in the design of future combination therapies.
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U2 - 10.1001/archinte.1973.00320090067007
DO - 10.1001/archinte.1973.00320090067007
M3 - Article
C2 - 4631683
AN - SCOPUS:0015592941
SN - 0003-9926
VL - 131
SP - 377
EP - 387
JO - Archives of internal medicine
JF - Archives of internal medicine
IS - 3
ER -