Single-Agent Therapy for Hodgkin's Disease

Stephen K. Carter, Robert B. Livingston

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

We have reviewed existing data on single drugs in the chemotherapy of Hodgkin's disease in order to place in perspective the recent results with regimens employing combinations of drugs. Combination chemotherapy, by historical comparison with single-drug therapy, is clearly superior in the induction of complete remission of disease. However, many single agents, particularly those in the antimetabolite and antibiotic classes of antitumor drugs, have been evaluated only minimally and may yet play important roles in the design of future combination therapies.

Original languageEnglish (US)
Pages (from-to)377-387
Number of pages11
JournalArchives of internal medicine
Volume131
Issue number3
DOIs
StatePublished - Mar 1973
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine

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