Abstract
The sera from patients with prostatic cancer have been observed to possess an unidentified factor capable of inhibiting the migration of leukocytes and the proliferative response to the nonspecific mitogen, phytohemagglutinin. Observation of inhibition of these two suggested in vitro correlates of cell-mediated immunologic responsiveness emphasizes (1) the importance to the adjunctive diagnosis and prognosis of patients with malignancy of identifying the presence of abnormal serum proteins, and (2) the role of humoral inhibitory or "immunoregulatory" factors as potential abrogators of mechanisms of host resistance, for example, immunologic surveillance, and thus the degree to which the host may respond to his tumor.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 22-29 |
| Number of pages | 8 |
| Journal | Urology |
| Volume | 6 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1975 |
| Externally published | Yes |
ASJC Scopus subject areas
- Urology